Istraživački tim sa Sveučilišta Mie u Japanu otkrio je da se rani embriji zebrice (embriji nekoliko sati nakon oplodnje) mogu sigurno ozračiti UVC od 278 nm.
UVC-LED diode od oko 260 nm koriste se za sterilizaciju jer induciraju i inaktiviraju oštećenje DNK od bakterija i virusa. Većina trenutačnih istraživanja usredotočuje se na učinak UVC-a s valnim duljinama ispod 240 nm (207 nm, 222 nm, 233 nm) na ubijanje novog koronavirusa. Međutim, postoji nekoliko studija o toksičnosti, sigurnosti i odgovoru organizama na UVC zračenje oko 280 nm.
Therefore, this time, a total of 16 irradiation doses were set in the range of 0.5 to 60 mJ/cm² using the irradiation device developed by the research group to irradiate 278 nm UVC, and zebrafish embryos were directly irradiated.
After 3 days of irradiation, the researchers evaluated the survival rate, hatching rate, heart rate, deformity rate, etc. of zebrafish embryos. The results found that all embryos remained alive under the irradiation dose below 4.5mJ/cm². However, when the dose reached 7.5 mJ/cm², the deformity rate significantly increased to 82 percent , and the survival rate decreased to 37 percent . Embryo death was observed if the dose was increased to 10 mJ/cm² and above.
Based on the above experimental results, the researchers determined that there is a biological defense system inside the zebrafish embryo, which can resist the damage caused by UVC irradiation to the greatest extent, and the limit dose that can resist UVC irradiation is 4.5 mJ/cm².
The researchers believe that the biological defense mechanism of zebrafish against UVC-induced DNA damage is that after zebrafish embryos are treated with UVC at a dose of 4.5 mJ/cm², the p53 signaling pathway in cells is immediately and urgently activated. Arrest, DNA repair, cell division/proliferation and damaged cell death in rapid response to stress. In addition, after 3 days of recovery, p53 variability was attenuated and instead activated the STAT signaling pathway, which continued to repair damaged DNA.
Rezultati istraživanja ove teme pružaju znanstvenu osnovu za sigurnost UVC-LED primijenjene na ljudsko tijelo. U isto vrijeme, istraživački je tim otkrio da je UVC prikladan za dezinfekciju bakterija i virusa, uključujući koronavirus, kao i za dezinfekciju u akvakulturi.
"Experts say UV" believes that: at the application level, the sterilization experience of UVC-LED is difficult to intuitively perceive, and consumers will have concerns about safety when using it. brings confidence.
GMKJ LED tehnologija duboko je uključena u zdrave i pametne izvore svjetlosti, pružajući tržištu cijeli niz UVA UVB UVC LED, infracrvenih IR LED VCSEL proizvoda i rješenja, te ima stotine visoko-partnera u zemlji i inozemstvu tržišta da zajednički promiču korištenje svjetlosne tehnologije za stvaranje zdravog i pametnog života. uzrok.
